Valerie Tyler is a 28-year-old organization freak who loves her 16-year-old sister Holly. Even if Holly is rambunctious. Spontaneous. Impulsive. Disconcerting. And definitely disorganized. Then Holly moves in with Val, and the sisters discover they may make better siblings than roomies.

Mike McNeil is a decorated New York City detective whose toughest assignment is himself. He's struggling to balance a challenging personal life with a job that leaves him wondering on a daily basis if he is the last sane person in New York. His unconventional approach to his job makes him a great cop, even on the most trying days. The only thing he can't figure out is why, if he's the only sane guy around, everyone's always looking at him like he's crazy.

Based on the bestselling book by Candace Bushnell, Sex and the City tells the story of four best friends, all single and in their late thirties, as they pursue their careers and talk about their sex lives, all while trying to survive the New York social scene.

Victor is a new student at Creekwood High School on his own journey of self-discovery, facing challenges at home, adjusting to a new city, and struggling with his sexual orientation. When it all seems too much, he reaches out to Simon to help him navigate the ups and downs of high school.

Workaholic Mike Flaherty is the Deputy Mayor of New York City, serving as Mayor Randall Winston's key strategist and much-needed handler. Mike runs the city with the help of his oddball staff: an anxious and insecure press secretary; a sexist, boorish chief of staff; an impeccably groomed gay activist running minority affairs; a sharp and efficient, man-crazy accountant; and an idealistic young speechwriter. Like Mike, they are all professionally capable but personally challenged.

Downtown is an animated series on MTV on urban life, based on interviews with real people. The show follows a diverse and multiracial cast who live in New York City, and presents their everyday lives through quirky, humorous, and imaginative perspectives from the characters. It was created by Chris Prynoski, a former animator on Beavis and Butt-Head and produced by David McGrath. In 2000, Downtown was nominated for an Emmy in the category of outstanding animated program. Downtown faced a similar fate to many of MTV's other cartoons - it only lasted one season. The use of an original score rather than licensed music makes a sanctioned DVD release unlikely. Some of the show's staff have gone on to work on the action animated series Megas XLR, which uses the same quirky humor found in Downtown as well as the character Goat, reprised by Scott Rienecker.