Being on call 24 hours a day enables practiced midwife Terri to hide her personal life and the depths of her hoarded home; as she constantly blames the hoarding on her busy schedule, past trauma surfaces to reveal the real reason for her disorder.

After discovering that his partner was stealing from him, undergoing a necessary heart surgery and facing many other adversities, successful artist Bob becomes a recluse, buying antiques to fill up his 7,000-square-foot Victorian mansion.

Between dumpster diving, weekly swap meet purchases and occasional yard sale finds, John collects a massive amount of clutter over the years and openly admits that he feels trapped by his hoard.

Destiny refuses to leave her home after a 2004 family tragedy causes her to "basically check out of life"; the extremely hoarded house comes to the attention of the landlords, and they want the place cleaned up or Destiny evicted.

David and Elizabeth have been co-dependent co-hoarders for as long as their adult children can remember. The couple had to remortgage their home because of their addiction to buying items sold on television, such as Tiffany-style lamps. David has more than 40 of these lamps, most of which have never been unboxed. The house is overrun with mice, and Elizabeth's doctor has threatened to report them to the city and have it condemned. David treats it all like a joke - but no one is laughing. With help from the Hoarders team, will this couple be able to let go of their things and hold onto each other?

As a child, Lori felt the high of buying 100 sticks of gum at a time or the same sweater in every color - but when she grew up and moved to the Canadian Far North, her home quickly became packed and unlivable. After her hoarding ended her relationship with the father of her son Tajko, she comforted herself with online shopping but now Tajko's future is at risk. With the help of the Hoarders crew, Lori is going to try and clean up her life - for the sake of both her and her son.

The only way David and Odette can enter or exit their 3,000 square foot home is by climbing a six-foot ladder into the kitchen. The couple live in what should be a dream home - an architecturally designed masterpiece with sweeping views of the Blue Mountains but instead, the house has become a nightmare. David has crammed it to the brim with stuff and Odette continues to add to the hoard with purchases from online auctions. The couple is on the brink of disaster and Odette is threatening to leave him if he can't clean up their home. With the help of the Hoarders team, can David and Odette unclutter their lives and get her hoarding disorder under control?

Coral is an educator above all, but she is also a fiber artist, musician, and a very talented herbalist. Her farmhouse is crammed full of art, crafts, musical instruments, board games, baskets and hundreds of containers filled with herbs and spices. Coral wants to turn her home into a community resource center where her knowledge can be passed on - but she needs help cleaning up her property. With the assistance of the Hoarders team, she intends to unclutter her life and get her hoarding disorder under control.