Half & Half is an American sitcom that aired on UPN from September 23, 2002, to May 15, 2006. The show focuses on the lives of two paternal half-sisters in their twenties who were estranged throughout their childhood, and are finally developing a close relationship. The series is set in San Francisco. It was the second-most-watched show on UPN's Monday night line-up and fourth overall on the network. The show was on The CW's first draft line-up in March 2006, but due to several circumstances—including The CW's contractual obligation to pick up Reba, the uncancelling of All of Us, and the pick-up of the Girlfriends spin-off The Game—Half & Half was left off the final Fall 2006 schedule and ended production. The series has aired in reruns on Global TV in Canada, Trouble in the UK and in local syndication in the United States. It also airs in the United States on TV One.

Valerie Tyler is a 28-year-old organization freak who loves her 16-year-old sister Holly. Even if Holly is rambunctious. Spontaneous. Impulsive. Disconcerting. And definitely disorganized. Then Holly moves in with Val, and the sisters discover they may make better siblings than roomies.

The two Warner Brothers Yakko and Wakko and their Warner sister Dot had been (supposedly) created in the 1930's, but their cartoons were too screwy for the general public to handle. The three Warners were locked up in the studio water tower until they escaped in the 90's. There, they run wild, causing chaos everywhere!

Enlisted is based on Kevin Biegel's relationship with his siblings. The comedy follows three very different brothers working together in the Army at a small base in Florida.

Hope, a down-to-earth, happily married mother of three has her tidy world turned upside down when her celebrity sister moves in. Faith was living the Hollywood life as a soap opera star before her character was killed off.

Three sisters (Prue, Piper and Phoebe) reunite and unlock their powers to become the Charmed Ones, the most powerful good witches of all time, whose prophesied destiny is to protect innocent lives from evil beings such as demons and warlocks. Each sister possesses unique magical powers that grow and evolve, while they attempt to maintain normal lives in modern day San Francisco.